The main objective of the course is to provide practical knowledge on the reactivity of organic molecules, catalysis and spectroscopic methodologies useful for the characterization of organic compounds (for example: IR, NMR, mass). The student will therefore develop the ability to apply catalytic organic transformations to the synthesis of simple compounds in 2-3 steps. Knowledge and understanding: understanding the chemical behavior and reactivity of aromatic compounds, carbonyl compounds with acidic protons. knowledge of the advanced principles of IR, NMR and mass spectroscopies. Laboratory activities therefore help the student to develop the ability to apply previous knowledge and to better understand the properties and reactivity of organic compounds and how to apply spectroscopic techniques for the characterization of organic compounds. Autonomy of judgment: the autonomy of judgment is developed in the laboratory with the teacher. This aspect will therefore be developed during the laboratory experiences, in which students should critically evaluate the results and evaluate the chosen experimental approach and during the critical elaboration of laboratory reports. Furthermore, this ability is increased during the exam preparation phase. Communication skills: during the lessons, students are required to interact with the teacher to acquire language skills and to learn to express themselves correctly. Students also have to prepare written reports on the experiences carried out in the laboratory. Communication skills are stimulated for the preparation of the test which is also based on an oral interview. Learning skills: this training objective is stimulated by the teacher during the laboratory experiences in which the concepts already presented in the classroom lessons are reviewed. Learning skills are assessed within the different assessment approaches provided.

It is suggested to attend the course of ADVANCED ORGANIC SYNTHESIS

Topics of the laboratory experiences: catalytic organic reactions. Separation of organic compounds. Thin layer and column chromatography. Solvent extraction. Use of different techniques for the identification of the isolated organic compounds. The contents of the teaching are consistent with the educational objectives as reported in the Teaching Regulations of the Course of Studies.

1. Identificazione spettrometrica di composti organici, R.M. Silverstein, F.X. Webster, D. J. Kiemle, Casa editrice Ambrosiana. 2. Organic Chemistry, Jonathan Clayden, Nick Greeves, Stuart Warren, Casa Editrice Piccin. 3. Reviews and recent research articles.

Laboratory experiences: Students will perform organo-, metal-based and photo-catalytic organic transformations. Specifically, students will carry out modern organic transformations. Organic compounds will be isolated from the reaction crudes through chromatographic techniques or other purification strategies. Products are characterized by IR, NMR and mass spectra. Students have to present a report for each experience and write the lab book.

Classroom Teaching and laboratory experiments carried out by the students. Writing of the laboratory notebook and of the reports of the laboratory experiments. Any changes these indications, which may become necessary to ensure the application of safety protocols related to the COVID19 emergency, will be communicated on the Department's and Degree Course websites and Lecture course Moodle page.

With reference to the Art. 9 paragraph 2 of the Teaching Regulations, attendance at the laboratory is mandatory, for which a participation in at least 80% of the scheduled exercise hours is required.

The student's assessment includes an oral interview. The student will have to comment on the laboratory experiences in particular by demonstrating that he has understood any errors in the report. The exam score is attributed by means of a mark, from 18 to 30, which takes into account the outcome of the oral exam, the evaluation of the reports, the laboratory notebook and the commitment shown by the student in carrying out the laboratory experiences.